I’ve made it to the 6 month mark with HGH, which is when all of the benefits should have kicked in. What have I experienced, both the good and the bad, after 180 days of TRT and HRT? I fully encourage anybody over the age of 45, if they’re feeling sluggish, to get their testosterone and IGF-1 levels checked. Testosterone Replacement Therapy and Human Growth Hormone Therapy could change your life for the better.