Easy, at home, testing. No laboratory blood draws. No prescription is necessary (except for those living in California and New York). A simple finger prick or saliva sample delivers reliable, accurate results. Mail your test kit to the laboratory in the postage-paid envelope and obtain your results within a few days – no waiting for a doctor. Private, affordable, and fast!
ESTRADIOL (E3) Blood Spot Test
The primary and most-potent form of estrogen produced by the body during reproductive years.
Estradiol is the predominant, and the most potent, circulating estrogen. It is mostly bound to sex hormone binding globulin in the blood. In reproductive age women, an excess of estradiol, relative to progesterone, can explain many symptoms including endometrial hyperplasia, pre-menstrual syndrome, fibrocystic breasts, and uterine fibroids. Women approaching menopause, whose estrogen levels swing from high to low while progesterone levels decline, can also experience symptoms of estrogen dominance, which include weight gain, fibrocystic and tender breasts, uterine fibroids, irritability, water retention, and thyroid problems. Estrogen dominance can lead to cancers of the uterus and breasts, and insulin resistance. With the onset of menopause, when ovarian estrogen and progesterone production decline, low estradiol levels lead to hot flashes, night sweats, vaginal dryness, sleep disturbances, foggy thinking, and bone loss. In men, too much estradiol, relative to testosterone levels, leads to feminizing effects such as breast enlargement. In healthy young men, testosterone is at its highest level and estradiol is very low. However, as men age, this shifts to a higher estradiol/testosterone ratio. Even if testosterone levels are normal, men can experience symptoms indicative of a functional testosterone deficiency because of the effects of higher than normal estradiol levels. The reference range for blood spot estradiol levels is 43—180 pg/mL in premenopausal women during the luteal phase; <10—49 pg/mL in postmenopausal women; and 12—56 pg/mL in men.
Blood Spot Test