Testosterone cypionate comes in an oil, usually cottonseed or grapeseed oil. I have read that some men get hypertensive from cottonseed oil, and it has resolved when switching to testosterone in a grapseed oil vehicle. This was of interest to me as I have developed hypertension since starting Trt, and it turns out I have been using testosterone in cottonseed oil. Havent switched yet but plan to when my current supply runs out. Could just be a coincidence, as I am 57 and maybe due for htn.